Neuroendocrine liver metastases: Vascular patterns on triple-phase MDCT are indicative of primary tumour location
| Autor: | Olivia Hentic, Maxime Ronot, Valérie Vilgrain, Marie-Pierre Vullierme, Francesco Cuccioli, Gaspard d’Assignies, Philippe Ruszniewski, Marco Dioguardi Burgio |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Computed tomography Enhancement pattern Ct attenuation Multimodal Imaging 030218 nuclear medicine & medical imaging Metastasis Young Adult 03 medical and health sciences 0302 clinical medicine Stomach Neoplasms Intestinal Neoplasms Multidetector Computed Tomography medicine Humans Radiology Nuclear Medicine and imaging Aged Aged 80 and over medicine.diagnostic_test business.industry Liver Neoplasms Magnetic resonance imaging General Medicine Middle Aged medicine.disease Neuroendocrine tumour Pancreatic Neoplasms Neuroendocrine Tumors 030220 oncology & carcinogenesis Female Radiology business Magnetic Resonance Angiography |
| Zdroj: | European Journal of Radiology. 89:156-162 |
| ISSN: | 0720-048X |
| DOI: | 10.1016/j.ejrad.2017.02.007 |
| Popis: | To re-evaluate and compare CT features of neuroendocrine liver metastases (NLM) from pancreatic (p) and enteric (e) gastroenteropancreatic (GEP) tumours.From 2006-2013, all patients with proven GEP-neuroendocrine tumours (NETs) with at least one NLM, no previous treatment were included. On unenhanced, arterial and portal phases, NLMs were characterized as hypo-, iso- or hyperattenuating in consensus by 2 radiologists blinded to clinical data. Enhancement patterns (EP) corresponded to the combination of arterial/portal CT attenuation.78 patients (43 men, 55%, mean 56±13 yo) and 559NLMs were analyzed. pNLMs were more frequently hypoattenuating on unenhanced CT than eNLMs (72% vs. 57%, p0.001). 70% of the lesions were hypervascular with no significant difference between pNLMs and eNLMs (p=0.32). eNLMs were more frequently hypoattenuating on portal phase than pNLMs (88% vs. 56%, p0.001). eNLMs were more frequently hyper/hypo than pNLMs (56% vs. 28%, p0.001). pNLMs were more frequently hyper/iso than eNLMs (33% vs. 8%, p0.001). Other NLMs showed various patterns, including hypo/hypo in 12%.Most NLMs of GEP tumours are hypervascular but the enhancement pattern on multiphasic CT depends on the primary tumour. These differences are helpful when the primary tumour has not been diagnosed. |
| Databáze: | OpenAIRE |
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