Celiac Disease in Children
| Autor: | Beth Loveridge-Lenza, Jennifer Jimenez, Karoly Horvath |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Glutens Biopsy Serum iga Disease Autoimmune enteropathy Gastroenterology Diet Gluten-Free Internal medicine medicine Humans Ingestion Protein Glutamine gamma Glutamyltransferase 2 In patient Intestinal Mucosa Child chemistry.chemical_classification biology business.industry Infant nutritional and metabolic diseases medicine.disease Gluten digestive system diseases Immunoglobulin A Intestines Celiac Disease chemistry Child Preschool Pediatrics Perinatology and Child Health biology.protein Female Antibody FIRST screening test business |
| Zdroj: | Pediatric Clinics of North America. 68:1205-1219 |
| ISSN: | 0031-3955 |
| DOI: | 10.1016/j.pcl.2021.07.007 |
| Popis: | Celiac disease is an autoimmune enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. In patients with suspected celiac disease, measurement of serum IgA antibodies to tissue transglutaminase-2 has a high sensitivity and specificity and is the first screening test that should be ordered. The diagnosis of celiac disease is based on the presence of mucosal damage in small intestinal biopsies in patients having circulating celiac disease-specific antibodies. Celiac disease management includes lifelong adherence to a gluten-free diet and continuous long-term follow-up. |
| Databáze: | OpenAIRE |
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