Histomorphological study of the preputial and clitoral glands in BALB/c mice with experimental Taenia crassiceps infections
| Autor: | C. Gabrion, Benjamin Gourbal |
|---|---|
| Přispěvatelé: | Parasitologie fonctionnelle et évolutive [2003-2006] (PFE), Centre National de la Recherche Scientifique (CNRS)-Université de Perpignan Via Domitia (UPVD), Université de Perpignan Via Domitia (UPVD)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
0106 biological sciences
Male Pathology Time Factors MESH: Research Support Non-U.S. Gov't 01 natural sciences Clitoris Mice Sexual Behavior Animal MESH: Animals Lymphocytes MESH: Sex Behavior Animal 0303 health sciences Mice Inbred BALB C biology [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE] MESH: Comparative Study MESH: Penis 3. Good health Specific Pathogen-Free Organisms medicine.anatomical_structure Female medicine.medical_specialty MESH: Sebaceous Glands Preputial gland MESH: Mice Inbred BALB C MESH: Atrophy 010603 evolutionary biology 03 medical and health sciences Sebaceous Glands Atrophy Sex Factors stomatognathic system MESH: Sex Factors MESH: Clitoris medicine Acinar cell Animals MESH: Mice Ecology Evolution Behavior and Systematics MESH: Taeniasis 030304 developmental biology Taeniasis Taenia crassiceps MESH: Time Factors Histology biology.organism_classification medicine.disease MESH: Male MESH: Specific Pathogen-Free Organisms Parasitology MESH: Lymphocytes MESH: Female Penis Hormone |
| Zdroj: | J Parasitol J Parasitol, 2006, 92 (1), pp.189-92 |
| Popis: | Male preputial and female clitoral glands of mice undergo development that depends on the level of hormones in the animal. Experimental infection with Taenia crassiceps cysticerci results in significant physiological modifications in the host. Here, we investigated the histomorphological alterations induced by the parasite in these pheromonal glands. Preputial and clitoral glands were recovered from mice at 15, 35, 50, and 70 days postinfection (DPI). The glands were examined macroscopically and microscopically after histological preparation. Male preputial glands show a marked atrophy 35 days after infection. This atrophy is the result of a disorganization of the acinus tissue structure. During the course of infection, the basal, intermediate, and mature acinar cell layers are reduced, and finally, at 70 DPI, the gland includes only the duct system and fibrotic structures. In contrast, females are not affected by the infection because no modifications were observed in the morphology or histology of the clitoral glands. A probable cause for such a divergence between infected male and female mice might be related to a sex steroid imbalance as described during T. crassiceps infection. |
| Databáze: | OpenAIRE |
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