Enhancing HIV Medication Adherence in India

Autor: Stephen M. Weiss, Deborah L. Jones, Ritu Nehra, Aman Sharma, Ryan Cook, Drenna Waldrop-Valverde, Szonja Vamos, Mahendra Kumar
Rok vydání: 2012
Předmět:
Zdroj: Journal of the International Association of Providers of AIDS Care (JIAPAC). 12:343-348
ISSN: 2325-9582
DOI: 10.1177/1545109712446177
Popis: Background: This pilot study evaluated an intervention designed to enhance adherence among those new to antiretroviral therapy. Methods: Participants (n = 80) were recruited from a hospital clinic in Chandigarh, India, and randomized to a 3-month group intervention or individual enhanced standard of care followed by crossover of condition and assessed over 6 months. Adherence was measured by prescription refill, pill count, and self-report. Results: At baseline, 56% of group condition (immediate intervention) and 54% of individual condition (delayed intervention) participants were nonadherent by pill count and 23% of group and 26% of individual condition participants self-reported skipping medication at least once over the last 3 months. From the postintervention to long-term follow-up, adherence in the group condition (immediate intervention) improved in comparison with adherence in the individual condition (delayed intervention; χ2 = 5.67, P = .02). Conclusions: Results support the use of interventions early in treatment to provide information and social support to establish long-term healthy adherence behaviors.
Databáze: OpenAIRE