Lingual Malignant Peripheral Nerve Sheath Tumor in a Chinese Pug Dog
| Autor: | Lois Roth-Johnson, Robert M. Baratt, Carroll J. Jones, Jennifer E. Rawlinson |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty Biopsy medicine.medical_treatment H&E stain Malignant peripheral nerve sheath tumor Malignancy Nerve Sheath Neoplasms Dogs Tongue medicine Animals Dog Diseases Granular cell tumor General Veterinary medicine.diagnostic_test business.industry Anatomy medicine.disease Treatment Outcome medicine.anatomical_structure Glossectomy Female business Neurilemmoma Nerve sheath neoplasm |
| Zdroj: | Journal of Veterinary Dentistry. 32:165-172 |
| ISSN: | 2470-4083 0898-7564 |
| DOI: | 10.1177/089875641503200303 |
| Popis: | A 9-year-old spayed/female Chinese Pug dog presented for evaluation of a mass located on the rostral aspect of the tongue. An incisional biopsy was acquired, submitted, and interpreted as a possible granular cell tumor based on hematoxylin and eosin, and periodic acid Schiff histopathologic staining characteristics. The diagnosis was supported by immunohistochemical evaluation that was positive for S-100, vimentin, and neuron-specific enolase. Based on the absence of mitotic figures in the incisional biopsy, a partial glossectomy was performed with gross margins of at least 1-cm. The excisional biopsy revealed significant features of malignancy, with neoplastic cells in close association with peripheral nerves, consistent with malignant peripheral nerve sheath tumor. Tumor-free margins were obtained, and the glossectomy had expected healing with no recurrence apparent 6-months following surgery. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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