Treatment of Vitamin and Mineral Deficiencies After Biliopancreatic Diversion With or Without Duodenal Switch: a Major Challenge
| Autor: | Jens Homan, Edo O. Aarts, Wendy Schijns, Ignace M. C. Janssen, Frits J. Berends, Hans de Boer |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Vitamin medicine.medical_specialty Pediatrics Duodenum Endocrinology Diabetes and Metabolism medicine.medical_treatment 030209 endocrinology & metabolism 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine mental disorders Vitamin D and neurology Humans Medicine In patient Biliopancreatic Diversion Retrospective Studies Minerals Nutrition and Dietetics business.industry Anastomosis Surgical Malnutrition Avitaminosis Middle Aged Duodenal switch Obesity Morbid Surgery chemistry Solubilization Treatment Schedule Female 030211 gastroenterology & hepatology Deficiency Diseases business Follow-Up Studies |
| Zdroj: | Obesity Surgery. 28:234-241 |
| ISSN: | 1708-0428 0960-8923 |
| DOI: | 10.1007/s11695-017-2841-0 |
| Popis: | Vitamin and mineral deficiencies are a major concern after biliopancreatic diversion (BPD) and BPD with duodenal switch (BPD/DS). Evidence-based guidelines how to prevent or how to treat deficiencies in these patients are currently lacking. The aim of the current study is to give an overview of postsurgical deficiencies and how to prevent and treat these deficiencies. Retrospective evaluation of a 1-year structured monitoring and treatment schedule for various deficiencies in 34 patients after BPD or BPD/DS. Patients were introduced into the program 12–90 months after surgery. Vitamin B1, B6, B9, and B12 deficiencies could be prevented by mean daily doses of 2.75 mg, 980 μg, 600 μg, and 350 μg, respectively. However, many patients continued to develop deficiencies of vitamin A, D, iron, calcium, and zinc despite major dose adjustments. Current observations suggest that at least total daily doses of 200 mg Fe in premenopausal women and 100 mg in men, 100 mg of Zinc, 3000 mg of calcium, and weekly doses of at least 50,000 IU solubilized vitamin A and vitamin D are needed to prevent the occurrence of major deficiencies. Exceptionally high supplementation doses are needed to prevent and treat vitamin and mineral deficiencies in patients after BPD or BPD/DS. Further refinement and simplification of treatment schedules is needed. Focus on improvement of compliance to treatment is recommended. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink