Asystolic cardiac arrest following liposomal amphotericin B infusion: anaphylaxis or compliment activation-related pseudoallergy?
Autor: | Joseph DeLuca, George P Drewett, Jason A Trubiano, Natasha E Holmes, Ana M Copaescu |
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Rok vydání: | 2021 |
Předmět: |
CARPA
Allergy Resuscitation Allergic reaction LAmB Case Report Ambisome 03 medical and health sciences 0302 clinical medicine medicine Mast cell activation business.industry Intradermal testing Pseudoallergy General Medicine RC581-607 medicine.disease Skin prick testing 030228 respiratory system 030220 oncology & carcinogenesis Immunology Liposomal amphotericin Immunologic diseases. Allergy business Anaphylaxis |
Zdroj: | Allergy, Asthma & Clinical Immunology, Vol 17, Iss 1, Pp 1-5 (2021) Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology |
ISSN: | 1710-1492 |
DOI: | 10.1186/s13223-021-00582-x |
Popis: | Allergic reaction to liposomal amphotericin B is rare. We report a case of cardiac arrest in a 64-year-old woman following liposomal amphotericin B infusion, requiring resuscitation. We also present the results of subsequent skin prick and intradermal testing to liposomal amphotericin on the patient and three healthy controls, highlighting the need for further research into the immunopathogenesis of this reaction. |
Databáze: | OpenAIRE |
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