Tissue distribution of some immune cells in bovine reproductive tract during follicular and luteal phase
| Autor: | Berna Güney Saruhan, Hakan Sağsöz, Narin Liman, Mehmet Erdem Akbalik |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Cell type Histology T-Lymphocytes Luteal Phase Luteal phase Biology Major histocompatibility complex Epithelium 03 medical and health sciences 0302 clinical medicine Immune system medicine Animals Reproductive system Instrumentation 030219 obstetrics & reproductive medicine Macrophages Reproduction Uterus Epithelial Cells Eosinophil Cell biology Medical Laboratory Technology 030104 developmental biology medicine.anatomical_structure Follicular Phase biology.protein Cattle Female Anatomy CD8 |
| Zdroj: | Microscopy Research and Technique. 81:315-331 |
| ISSN: | 1059-910X |
| DOI: | 10.1002/jemt.22983 |
| Popis: | More recent studies indicate that immune cells which secrete their secretory products or cytokines play an important role in reproductive system. In our study, immune cell populations (CD8(+) T lymphocytes, CD68(+) macrophages, plasma cells, siderophages, eosinophils) and expression of major histocompatibility complex (MHC) class I and class II were examined in female reproductive tract during follicular (n=13) and luteal phase (n=10). Plasma cells and eosinophil granulocytes are present in few numbers in luminal epithelium, but abundant in longitudinal muscle layer of uterus, whereas siderophages are the dominant cell type in stroma. Moreover, MHC-I and -II+ cells are expressed by individual cells in organ layers, while CD8(+) T cells and CD68(+) macrophages are dominant in epithelium and muscle layer, respectively. In conclusion, we did not found significant changes in immune cells according to follicular and luteal phases, but localization and numbers in each organ have changed according to both organ and layers. These results indicate that these factors may play a crucial role not only to generate an immune response but also to have a role in regulation of physiological functions in female reproductive organs. |
| Databáze: | OpenAIRE |
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