Adrenal Response to Hypophysectomy in the Newborn Dog

Autor: Ralph A. Kinsella, Faith Ellen Francis, Gerhard H. Muelheims
Rok vydání: 1969
Předmět:
Zdroj: Experimental Biology and Medicine. 131:1389-1392
ISSN: 1535-3699
1535-3702
DOI: 10.3181/00379727-131-34114
Popis: SummaryHypophysectomy in the newborn dog results in a prompt fall in the secretory rate of cortisol during collection of adrenal effluent blood. Due to the rapid rate of clearance of ACTH, lowest secretory rates were expected at 2–5 hr after hypophysectomy but, at 16–20 hr, an even lower rate was found. This unexplained observation was significant. The procedure of hypophysectomy recommends itself as a valuable means of exploring the endocrinologic status of the newborn.
Databáze: OpenAIRE