The Effect of Resveratrol on the Cardiovascular System from Molecular Mechanisms to Clinical Results
| Autor: | Laszlo Deres, Roland Gal, Tamas Habon, Kalman Toth, Robert Halmosi |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19) QH301-705.5 Energy metabolism Anti-Inflammatory Agents heart failure Review Resveratrol resveratrol Bioinformatics Cardiovascular System Catalysis Antioxidants Inorganic Chemistry chemistry.chemical_compound Medicine Animals Humans oxidative stress Biology (General) Physical and Theoretical Chemistry QD1-999 Molecular Biology Beneficial effects Spectroscopy business.industry Organic Chemistry COVID-19 General Medicine Computer Science Applications COVID-19 Drug Treatment cardiovascular diseases Clinical trial Chemistry chemistry inflammation Cell longevity Signal transduction business |
| Zdroj: | International Journal of Molecular Sciences International Journal of Molecular Sciences, Vol 22, Iss 10152, p 10152 (2021) |
| ISSN: | 1422-0067 |
| Popis: | Cardiovascular diseases are the leading causes of death worldwide. The cardioprotective effects of natural polyphenols such as resveratrol (3,5,4-trihydroxystilbene) have been extensively investigated throughout recent decades. Many studies of RES have focused on its favorable effects on pathological conditions related to cardiovascular diseases and their risk factors. The aim of this review was to summarize the wide beneficial effects of resveratrol on the cardiovascular system, including signal transduction pathways of cell longevity, energy metabolism of cardiomyocytes or cardiac remodeling, and its anti-inflammatory and antioxidant properties. In addition, this paper discusses the significant preclinical and human clinical trials of recent years with resveratrol on cardiovascular system. Finally, we present a short overview of antiviral and anti-inflammatory properties and possible future perspectives on RES against COVID-19 in cardiovascular diseases. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|