Polydopamine-functionalized graphene nanoplatelet smart conducting electrode for bio-sensing applications
| Autor: | Francis D. Krampa, Gordon A. Awandare, Prosper Kanyong, Yaw Aniweh |
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| Rok vydání: | 2020 |
| Předmět: |
Detection limit
biology Chemistry General Chemical Engineering education 02 engineering and technology General Chemistry Polyethylene glycol 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Dielectric spectroscopy lcsh:Chemistry chemistry.chemical_compound lcsh:QD1-999 PEDOT:PSS Chemical engineering Electrode biology.protein Glucose oxidase Cyclic voltammetry 0210 nano-technology Biosensor |
| Zdroj: | Arabian Journal of Chemistry, Vol 13, Iss 1, Pp 1669-1677 (2020) |
| ISSN: | 1878-5352 |
| DOI: | 10.1016/j.arabjc.2018.01.001 |
| Popis: | The development of a novel polydopamine (PDA)-functionalized graphene nanoplatelets (GNPs)-based disposable sensor is described. The sensor was fabricated by drop-coating PDA@GNPs in polyethylene glycol (PEG) and poly(3,4-ethylenedioxythiophene (PEDOT):poly(styrenesulfonate) (PSS) aqueous suspension onto the working area of a screen-printed electrode (SPE). The final sensor, designated as PDA@GNPs/PPP/SPE, was characterized by scanning electron microscopy (SEM), Raman spectroscopy, Faradaic electrochemical impedance spectroscopy (FEIS) and cyclic voltammetry (CV). Mediated detection of hydrogen peroxide (H2O2) via the redox properties of PDA was achieved. It showed excellent selectivity and sensitivity towards H2O2 with a limit of detection and sensitivity of 0.55 µM (S/N = 3) and 3.0 µA mM−1 cm−2, respectively. Thereafter, glucose oxidase (GOx) was immobilized onto the electrode to develop GOx/PDA@GNPs/PPP/SPE sensor. The glucose biosensor exhibited a limit of detection of 0.25 μM (S/N = 3) and a sensitivity of 0.51 μA μM−1 cm−2; thus, proving its potential suitability for bio-sensing applications. Keywords: Polyethylene glycol, Screen-printed electrodes, Bio-sensing, Mediated sensors, Thin films, Dopamine, Organocatalysts |
| Databáze: | OpenAIRE |
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