Incidence of Adverse Contrast Reaction Following Nonintravenous Urinary Tract Imaging
| Autor: | Gopal N. Gupta, Paul C. Kuo, Robert C. Flanigan, Anai N. Kothari, Matthew A.C. Zapf, Eric J. Kirshenbaum, Robert H. Blackwell |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Radiographic contrast media Percutaneous Databases Factual Drug-Related Side Effects and Adverse Reactions Urology Urinary system Laryngismus 030232 urology & nephrology Contrast Media Pulmonary Edema California 03 medical and health sciences 0302 clinical medicine Edema Humans Medicine Laryngospasm Angioedema Anaphylaxis Aged Upper urinary tract Aged 80 and over business.industry Incidence Shock Urography Middle Aged medicine.disease Surgery 030220 oncology & carcinogenesis Florida Female Hypotension medicine.symptom business Pyelogram |
| Zdroj: | European Urology Focus. 3:89-93 |
| ISSN: | 2405-4569 |
| DOI: | 10.1016/j.euf.2016.01.009 |
| Popis: | Adverse reactions (ARs) to intravenous (IV) radiographic contrast range from mild urticaria to life-threatening anaphylaxis. Intraluminal contrast dye is routinely used in the urinary tract with a minimal perceived risk of AR. We used the Healthcare Cost and Utilization Project State Inpatient Databases for California and Florida from 2007 to 2011 to identify patients who received urinary tract contrast dye for retrograde pyelography, percutaneous pyelography, retrograde/other cystogram, and ileal conduitogram. After excluding patients who had received IV contrast for other radiologic studies, ARs to contrast were identified by a composite end point of diagnoses not present on admission including shock, anaphylaxis, iatrogenic hypotension, urticaria, angioedema, laryngospasm, laryngeal edema, and/or a new diagnosis of contrast reaction. Overall, 76 174 patients were included who had undergone non-IV urinary tract imaging, 367 (0.48%) of whom developed an AR. On multivariate analysis, receipt of contrast in the lower urinary tract (odds ratio [OR]: 1.8; p =0.04) or upper urinary tract by retrograde pyelography (OR: 1.6; p =0.04) or antegrade pyelography (OR: 2.0; p =0.007) increased the risk of AR compared with control patients. The use of contrast dye in the urinary tract is associated with a low, but present risk of AR. Patient summary We looked at patients who underwent a urologic procedure using radiographic contrast media in the urinary tract. Although adverse reactions (ARs) may occur with the use of contrast media in the urinary tract, these reactions are experienced by a minority of patients (approximately 1 in 200). In addition, we found that an allergy to intravenous contrast does not increase a patient's risk of an AR to contrast within the urinary tract. |
| Databáze: | OpenAIRE |
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