Squamous cell metaplasia of the nasopharyngeal epithelium and its association with adult-onset otitis media with effusion
| Autor: | Harun Doğru, Mustafa Tüz, Hasan Yasan, Özden Çandir, Metin Ciris |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Adolescent Eustachian tube Biopsy Neck mass Nasopharyngeal neoplasm Tuberculosis Lymph Node Lymphadenitis Recurrence Nasopharynx Metaplasia otorhinolaryngologic diseases Humans Medicine Aged medicine.diagnostic_test Otitis Media with Effusion business.industry Eustachian Tube Endoscopy Epithelial Cells General Medicine Middle Aged medicine.disease Middle Ear Ventilation Squamous metaplasia medicine.anatomical_structure Otitis Otorhinolaryngology Effusion Lymphatic Metastasis Female Nasal Cavity medicine.symptom business Neck Follow-Up Studies |
| Zdroj: | Acta Oto-Laryngologica. 125:580-584 |
| ISSN: | 1651-2251 0001-6489 |
| DOI: | 10.1080/00016480510026917 |
| Popis: | The common association between adult-onset otitis media with effusion (AO-OME) and squamous cell metaplasia (SCM) of the epithelium of Rosenmüller's fossa, which is near the Eustachian tube orifice, implies the predictive role of metaplasia, which probably compromises the drainage function of the middle ear.To determine the effects of nasopharyngeal epithelial changes (SCM) on AO-OME. AO-OME is a multifactorial and insidious disease that may necessitate detailed investigation, i.e. biopsy of the nasopharynx, because of possible underlying nasopharyngeal malignancy.Fifty-two patients with AO-OME (study group) and 29 with a unilateral neck mass in the posterior triangle without AO-OME (control group) were enrolled. Nasopharyngeal biopsies taken from all subjects were evaluated with regard to surface epithelial changes of the nasopharynx.Nasopharyngeal biopsies revealed SCM in 34/52 patients (65%) in the study group and 9/29 (31%) in the control group (p0.05). During the follow-up period, recurrence of effusion occurred in 56% of the group with SCM and 22% of the group without it. |
| Databáze: | OpenAIRE |
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