Repeatability of selective laser trabeculoplasty
| Autor: | Tony Realini, Julia Polat, Lindsay Grantham, Kenneth Mitchell |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Reoperation medicine.medical_specialty Intraocular pressure Time Factors genetic structures Selective laser trabeculoplasty Glaucoma Trabeculectomy Lasers Solid-State 03 medical and health sciences Cellular and Molecular Neuroscience Tonometry Ocular 0302 clinical medicine Ophthalmology Chart review medicine Humans In patient Postoperative Period Intraocular Pressure Aged Retrospective Studies Aged 80 and over business.industry Absolute level Repeatability Middle Aged medicine.disease eye diseases Sensory Systems Treatment Outcome 030221 ophthalmology & optometry Female sense organs Laser Therapy business 030217 neurology & neurosurgery Median survival Glaucoma Open-Angle Follow-Up Studies |
| Zdroj: | The British journal of ophthalmology. 100(10) |
| ISSN: | 1468-2079 |
| Popis: | Purpose To determine the intraocular pressure (IOP)-lowering efficacy of repeat 360° selective laser trabeculoplasty (SLT) in patients with open-angle glaucoma having undergone prior successful 360° SLT. Methods A retrospective chart review of 38 eyes of 38 patients with open-angle glaucoma (primary, pseudoexfoliation or pigmentary glaucoma) uncontrolled on medical therapy who had undergone two successive 360° SLT treatments, in whom first SLT was deemed clinically successful through a minimum of 6 months follow-up and who were followed for a minimum of 30 days after second SLT. Mean IOP at each postoperative time point (1, 3, 6, 12, 18 and 24 months) was compared with baseline using paired t tests. IOP changes after initial and repeat SLT were evaluated separately. Results Mean (SD) baseline IOP before initial SLT was 21.6 (4.8) mm Hg. Mean IOP following initial SLT was significantly below baseline through 24 months of follow-up, with mean IOP at months 1–24 ranging from 15.9 to 18.6 mm Hg. Mean baseline IOP before repeat SLT was 19.1 (3.9) mm Hg, with a significant reduction in IOP from baseline through 24 months follow-up with mean IOP ranging from 14.7 to 17.0 mm Hg. Kaplan–Meier survival analysis showed longer median survival time for repeat SLT compared with initial SLT. No safety issues were observed with repeat SLT. Conclusions Repeat SLT can restore IOP control in eyes with open-angle glaucoma that have previously undergone successful initial SLT. Repeat SLT achieves comparable absolute level of IOP control achieved by initial SLT. |
| Databáze: | OpenAIRE |
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