Assessing the Relationship between Chronic Lymphoid Leuke-mia Mortality Rates and Human Development Index: A 26-Year Trend Analysis Using Location-Scale Mixed Effects Model
| Autor: | Alireza Moghisi, Farid Zayeri, Parisa Rezanejad Asl |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Mixed model
Human development index business.industry Mortality rate Public Health Environmental and Occupational Health Chronic lymphoid leukemia Trend analysis Standardized mortality ratio Scale (social sciences) hemic and lymphatic diseases Medicine Original Article Statistical analysis Human Development Index Public aspects of medicine RA1-1270 business Demography |
| Zdroj: | Iranian Journal of Public Health, Vol 50, Iss 3 (2021) Iranian Journal of Public Health |
| ISSN: | 2251-6093 2251-6085 |
| Popis: | Background: Chronic lymphoid leukemia (CLL) is one of the most prevalent types of leukemia, which is responsible for a remarkable mortality rate in the world. This study aimed to investigate the global trend of this cancer from 1990 to 2015 and to determine the relationship between trend of CLL mortality rate and Human Development Index (HDI) throughout the world. Methods: The age-standardized mortality rate data of all countries of the world (per 100,000) were extracted from the GBD database. In addition, the HDI values for the studied countries in different years were obtained from the UNDP database. The statistical analysis was performed using the mixed-effects location-scale model in the SAS software, version 9.4. Results: The findings of the statistical modeling showed a downward slope for CLL Age Standardized Mortality Rate (ASMR) for total world countries ( ˆ 0.002 ). We also find a significant association between CLL ASMR and HDI. Countries with higher HDI had higher level of CLL ASMR in years 1990 to 2015 with a negative slope. Furthermore, countries with lower HDI had Lower level of CLL ASMR with rather fixed rates in this period. Conclusion: These findings showed a decreasing trend of global CLL ASMR in the previous decades, although, the fixed trend of CLL ASMR in countries with low HDI is worrisome. The health policymakers should make more efforts to decrease the mortality due to this cancer in these countries. |
| Databáze: | OpenAIRE |
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