Riesgo de recurrencia y de nuevas neoplasias cutáneas malignas en sujetos mexicanos con carcinoma basocelular
| Autor: | Alberto Tlacuilo-Parra, Guillermo Solís Ledesma, Elizabeth Guevara-Gutiérrez, José F Ruiz-González, Mercedes Hernández-Torres |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Adult
Male Risk 030213 general clinical medicine medicine.medical_specialty Skin Neoplasms Adolescent Antineoplastic Agents 030204 cardiovascular system & hematology Cryosurgery Young Adult 03 medical and health sciences 0302 clinical medicine Recurrence Electrocoagulation medicine Carcinoma Humans Basal cell Basal cell carcinoma In patient Aged Retrospective Studies Aged 80 and over Gynecology Imiquimod business.industry Margins of Excision Neoplasms Second Primary Middle Aged Mohs Surgery medicine.disease Carcinoma Basal Cell Carcinoma Squamous Cell Female Surgery business After treatment |
| Zdroj: | Cirugía y Cirujanos. 86 |
| ISSN: | 0009-7411 |
| DOI: | 10.24875/ciru.18000190 |
| Popis: | Introduccion El carcinoma basocelular (CBC) es la neoplasia cutanea maligna mas comun. Objetivo se investigo el riesgo de recurrencia y de nueva neoplasia cutanea maligna despues del tratamiento de CBC. Metodo Estudio retrospectivo. Fueron identificados los pacientes con diagnostico histopatologico de CBC primario, de enero de 2007 a diciembre de 2009, y se revisaron los expedientes para investigar el numero de recurrencias, la localizacion, el tipo de tratamiento y la variante histopatologica, determinando nuevas neoplasias cutaneas malignas. El analisis incluyo estadistica descriptiva e inferencial, considerando significativa una p < 0.05. Resultados Se incluyeron 397 pacientes, con un seguimiento promedio de 4 ± 1.5 anos. La recurrencia se presento en el 4% y se relaciono con un mayor tiempo de evolucion (36 vs. 32 meses; p = 0.04) y haber sido tratado mediante tecnicas destructivas (electrofulguracion, criocirugia o imiquimod; 31 vs. 4%; p = 0.0004). No hubo relacion con la localizacion ni con la variante histopatologica. El riesgo de desarrollar una nueva neoplasia maligna fue del 25%, y de ellas el 66% correspondio a un nuevo CBC y el 30% a carcinoma espinocelular. Conclusiones Es importante el seguimiento de los pacientes con CBC para identificar tanto las recurrencias como las nuevas neoplasias malignas, independientemente de la localizacion y de la variante histopatologica del primario. El tratamiento con tecnicas quirurgicas condiciona una menor recaida que las tecnicas destructivas. Introduction Basal cell carcinoma (BCC) is the most common skin malignant neoplasm. Objective. Investigate the risk of recurrence and of new skin malignant neoplasms, after treatment of BCC. Method Retrospective study. We examined the files of patients with histopathological diagnosis of primary BCC, between January 2007 and December 2009, and we investigate number of recurrences and their relationship with localization, treatment type, and histopathological variant, and the number of new skin malignant neoplasms. For analysis, we employed descriptive and inferential statistics; p < 0.05 was considered significant. Results A total of 397 patients, with an average follow-up of 4 ± 1.5 years. Recurrences presented in 4%. Recurrences were related with longer time of evolution (36 vs. 32 months; p = 0.04) and treatment with destructive techniques (electrofulguration, cryosurgery or imiquimod; 31 vs. 4%; p < 0.001). There was no relationship with localization, or the histopathological variant. The risk of developing a new malignant neoplasm was 25%; 66% corresponded to a new BCC and 30% to squamous cell carcinoma. Conclusions Follow-up of patients with BCC should be conducted independently of their localization and histopathological variant, especially in patients with greater evolution time, principally with surgical techniques. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|