A case of a duodenal gastrointestinal stromal tumor diagnosed with the aid of diffusion-weighted magnetic resonance imaging
Autor: | Masao Okubo, Kenichiro Nakachi, Kouichi Tamura, Hiroshi Mitsui, Takeo Suzuki, Hiroo Terashima, Naoaki Hashimoto, Makoto Ishikawa, Eriko So, Kanetoshi Sato, Junichi Okuda, Hajime Yamaguchi, Yukiko Kishida, Katsuya Kobayashi, Toru Matsui, Kenichiro Sekigawa |
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Rok vydání: | 2009 |
Předmět: |
Gastrointestinal tract
medicine.medical_specialty medicine.diagnostic_test GiST business.industry Esophagogastroduodenoscopy Gastroenterology Colonoscopy Magnetic resonance imaging General Medicine medicine.anatomical_structure Melena Duodenum Medicine Radiology medicine.symptom Stromal tumor business |
Zdroj: | Clinical Journal of Gastroenterology. 2:384-387 |
ISSN: | 1865-7265 1865-7257 |
Popis: | Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumor of gastrointestinal tract, and bleeding is among the primary symptoms. If the tumor is located in the small intestine, diagnosis might be difficult because of its inaccessibility by endoscope. This report presents a case of duodenal GIST diagnosed with the aid of diffusion-weighted (DW) magnetic resonance imaging (MRI). A 66-year-old male was admitted to the hospital because of shortness of breath and melena. The patient demonstrated marked anemia. Esophagogastroduodenoscopy and colonoscopy revealed no involvement of the mucosa of the gastrointestinal tract in regard to the observed bleeding. Thereafter, computed tomography was done and showed a tumorous lesion 4.2 cm in diameter located around the ligament of Treitz. The area showed significant high intensity by DW-MRI, strongly suggesting malignant character. Examination with a long endoscope demonstrated a large submucosal tumor with wide ulceration located at the third portion of the duodenum. The biopsy sample contained spindle-shaped cells that were positive for CD34 and c-kit on histochemistry, and the tumor was diagnosed as GIST. The patient underwent surgery and survived for 16 months without any recurrence. |
Databáze: | OpenAIRE |
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