Hearing loss and quality of life in survivors of paediatric CNS tumours and other cancers
| Autor: | Annette, Weiss, Grit, Sommer, Christina, Schindera, Laura, Wengenroth, Axel, Karow, Manuel, Diezi, Gisela, Michel, Claudia E, Kuehni, N, von der Weid |
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| Přispěvatelé: | Ansari Djaberi, Marc Georges |
| Rok vydání: | 2018 |
| Předmět: |
Male
Quality of Life/psychology Pediatrics medicine.medical_specialty Hearing loss Hearing Loss/diagnosis Childhood Cancer Survivor Study Logistic regression Central Nervous System Neoplasms 03 medical and health sciences Social support 0302 clinical medicine Quality of life Cancer Survivors Intervention (counseling) Surveys and Questionnaires Cancer Survivors/psychology otorhinolaryngologic diseases Medicine Humans Hearing Loss business.industry 030503 health policy & services Central Nervous System Neoplasms/complications/pathology Public Health Environmental and Occupational Health Cancer medicine.disease humanities 030220 oncology & carcinogenesis Child Preschool Quality of Life Female medicine.symptom 0305 other medical science business Complication |
| Zdroj: | Quality of Life Research, Vol. 28, No 2 (2019) pp. 515-521 |
| ISSN: | 1573-2649 0962-9343 |
| Popis: | PURPOSE Hearing loss, a complication of cancer treatment, may reduce health-related quality of life (HRQoL), especially in childhood cancer survivors of central nervous system (CNS) tumours who often have multiple late effects. We examined the effect of hearing loss on HRQoL in young survivors of CNS and other childhood cancers. METHODS Within the Swiss Childhood Cancer Survivor Study, we sent questionnaires about hearing loss and HRQoL (KIDSCREEN-27) to parents of survivors aged 8-15 years. We stratified the effect of hearing loss on HRQoL by cancer diagnosis, using multivariable logistic regression and adjusting for sociodemographic and clinical factors. RESULTS Hearing loss was associated with impaired physical well-being [unadjusted estimated differences - 4.6 (CI - 9.2, - 0.1); adjusted - 4.0 (CI - 7.6, - 0.3)] and peers and social support [unadjusted - 6.7 (CI - 13.0, - 0.3); adjusted - 5.0 (CI - 10.5, 0.9)] scores in survivors of CNS tumours (n = 123), but not in children diagnosed with other cancers (all p-values > 0.20, n = 577). CONCLUSION Clinicians should be alert to signs of reduced physical well-being and impaired relationships with peers. Especially survivors of CNS tumours may benefit most from strict audiological monitoring and timely intervention to mitigate secondary consequences of hearing loss on HRQoL. |
| Databáze: | OpenAIRE |
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