tDCS effects on task-related activation and working memory performance in traumatic brain injury: A within group randomized controlled trial
| Autor: | Travis A Wearne, Emma J. Kornfeld, Skye McDonald, Colleen Loo, Emily J Wilson, Jodie A Logan, Donel Martin, Frances M. De Blasio, Jacqueline A. Rushby |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Traumatic brain injury medicine.medical_treatment Prefrontal Cortex Transcranial Direct Current Stimulation Task (project management) law.invention Arousal Physical medicine and rehabilitation Cognition Arts and Humanities (miscellaneous) Randomized controlled trial law Brain Injuries Traumatic Medicine Humans Applied Psychology Transcranial direct-current stimulation Working memory business.industry Rehabilitation medicine.disease Neuropsychology and Physiological Psychology Memory Short-Term business |
| Zdroj: | Neuropsychological rehabilitation. 31(5) |
| ISSN: | 1464-0694 |
| Popis: | Non-invasive transcranial direct current stimulation (tDCS) has been reported to facilitate working memory in normal adults. There is some evidence in people with Traumatic Brain Injury (TBI) but overall evidence is mixed. This study aimed to address shortcomings of prior study designs in TBI to examine whether a single dose of tDCS would lead to benefits in working memory. Thirty people with severe, chronic TBI were administered a single session of either anodal tDCS (2 mA for 20 min) or sham tDCS (2 mA for 30 s), in a counterbalanced order, over the left parietal cortex while performing 1-back and 2-back working memory tasks. Skin conductance levels were examined as a measure of task activated arousal, a possible functional analogue of cortical excitability. We found that tDCS led to no improvements in accuracy on the working memory tasks. A slight increase in variability and reaction time with tDCS was related to decreased task activated arousal. Overall, this study yielded no evidence that a single session of tDCS can facilitate working memory for people with TBI. |
| Databáze: | OpenAIRE |
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