Considering intellectual, in addition to financial, conflicts of interest proved important in a clinical practice guideline: a descriptive study
| Autor: | Gordon H. Guyatt, Elie A. Akl, Holger J. Schünemann, Hiba Abou-Haidar, Pierre El-Hachem, Ignacio Neumann |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Finance
Conflict of Interest Epidemiology business.industry media_common.quotation_subject Conflict of interest Thrombosis Disclosure Guideline Unit of analysis Clinical Practice Fibrinolytic Agents Voting Practice Guidelines as Topic Humans Medicine Descriptive research business Consensus development Fibrinolytic agent media_common |
| Zdroj: | Journal of Clinical Epidemiology. 67:1222-1228 |
| ISSN: | 0895-4356 |
| DOI: | 10.1016/j.jclinepi.2014.05.006 |
| Popis: | Objectives The American College of Chest Physicians Antithrombotic Guidelines ninth iteration placed restrictions on panelists with recommendations on which they disclosed a primary conflict of interest (COI). We aimed to describe panelists' financial and intellectual COI and evaluate to what extent, beyond assessing financial COI, assessing intellectual COI affected COI management. Study Design and Setting We classified financial and intellectual COI into primary (causes voting restriction) and secondary (no restrictions). We analyzed disclosures respectively with panelists and recommendations as units of analysis. Results One hundred two panelists made 4,030 disclosures for 431 recommendations. The median number (and range) of panelists per recommendation who disclosed the various categories of COI was 0 (0–5) for primary financial COI, 0 (0–4) for secondary financial COI, 0 (0–7) for primary intellectual COI, and 1 (0–6) for secondary intellectual COI. Of the 431 recommendations, 63 (15%) had at least one panelist with a primary intellectual COI but no primary financial COI. Conclusion COI had a relatively low prevalence and a skewed distribution, many panelists with none and some with many disclosures. A substantial number of disclosures should have resulted in restrictions based on intellectual COI in the absence of financial COI. |
| Databáze: | OpenAIRE |
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