Characterization and Evaluation of Injectable Biodegradable Polymer Multimodality Radiologic Markers in an In Vivo Murine Model

Autor:	Eliel Ben-David, Abraham J. Domb, Haixing Liao, Awanish Kumar, Issac Nissenbaum, Matthias Stechele, Peter Siman, Natalie Greenbaum, Naama Lev Cohain, S. Nahum Goldberg
Rok vydání:	2022
Předmět:	Biomaterials Disease Models Animal Mice Polymers and Plastics Iron Materials Chemistry Animals Bioengineering Prostheses and Implants Magnetic Resonance Imaging Polyglycolic Acid
Zdroj:	Biomacromolecules. 23:1672-1679
ISSN:	1526-4602 1525-7797
Popis:	Biodegradable polymer clips as multidimensional soft tissue biopsy markers were developed with better biocompatibility and imaging features. Unlike the commercially available metallic biopsy markers, the developed polymer clips are temporary implants with similar efficacies as metal markers in imaging and detection and get absorbed within the body with time. Herein, we evaluate the degradation rate of three resorbable polymer-based marker compounds in an in vivo murine model. Three polymers, abbreviated as Polymer A (PLGA poly(lactic
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef04f3cdc1fec1b70bf82b18a5631c37 https://doi.org/10.1021/acs.biomac.1c01570 Zobrazit plný text záznamu