Simultaneous topography-guided photorefractive keratectomy followed by corneal collagen cross-linking for keratoconus
| Autor: | George A. Kounis, George D. Kymionis, Dimitra M. Portaliou, Georgios A. Kontadakis, Aliki N Limnopoulou, Michael A. Grentzelos |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Keratoconus medicine.medical_specialty genetic structures Ultraviolet Rays medicine.medical_treatment Eye disease Corneal Stroma Riboflavin Corneal collagen cross-linking Visual Acuity Refraction Ocular Photorefractive Keratectomy Phototherapeutic keratectomy Young Adult Cornea Ophthalmology medicine Humans Prospective Studies Dioptre Photosensitizing Agents medicine.diagnostic_test business.industry Corneal Topography Middle Aged Corneal topography medicine.disease Combined Modality Therapy eye diseases Photorefractive keratectomy Surgery medicine.anatomical_structure Cross-Linking Reagents Treatment Outcome Photochemotherapy Female Lasers Excimer Collagen business Follow-Up Studies |
| Zdroj: | American journal of ophthalmology. 152(5) |
| ISSN: | 1879-1891 |
| Popis: | To present the long-term results after simultaneous photorefractive keratectomy followed by corneal collagen cross-linking for keratoconus.Prospective, interventional, consecutive case series.In this study, 26 patients (31 eyes) with progressive keratoconus were included. All patients underwent customized topography-guided photorefractive keratectomy immediately followed by corneal collagen cross-linking with the use of riboflavin and ultraviolet A irradiation. Epithelium was removed by transepithelial phototherapeutic keratectomy in all cases.Mean follow-up was 19.53 ± 3.97 months (range, 12 to 25 months). Mean preoperative spherical equivalent was -2.3 ± 2.8 diopters (D), whereas at the last follow-up examination, it was significantly (P.001) reduced to -1.08 ± 2.41 D. Logarithm of the minimal angle of resolution uncorrected and best-corrected visual acuity were reduced significantly by 0.46 and 0.084 (P.001), respectively, at the last follow-up examination. Finally, mean steep and flat keratometry readings were reduced by 2.35 (P.001) and 1.18 (P = .013) at the last follow-up examination.Simultaneous photorefractive keratectomy followed by corneal collagen cross-linking seems to be a promising treatment alternative in our series of keratoconic patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect