Antiplasmodial and Cytotoxic Activity of Raw Plant Extracts as Reported by Knowledgeable Indigenous People of the Amazon Region (Vaupés Medio in Colombia)

Autor:	Adriana Pabón, Felipe Cardona, Alexandra Ríos, Briegel De Las Salas, Silvia Blair, Ena López, Otoniel Ramirez
Rok vydání:	2016
Předmět:	030231 tropical medicine Plasmodium falciparum Pharmaceutical Science Microbial Sensitivity Tests Colombia 01 natural sciences Indigenous Analytical Chemistry 03 medical and health sciences Antimalarials 0302 clinical medicine Chloroquine parasitic diseases Drug Discovery medicine Humans Medicinal plants Pharmacology Plants Medicinal Traditional medicine biology 010405 organic chemistry Amazon rainforest Plant Extracts Indians South American Organic Chemistry Hep G2 Cells biology.organism_classification medicine.disease 0104 chemical sciences Complementary and alternative medicine Molecular Medicine Medicine Traditional Malaria medicine.drug
Zdroj:	Planta medica. 82(8)
ISSN:	1439-0221
Popis:	The in vitro antiplasmodial activity of 122 raw extracts prepared in ethanol and water from 35 medicinal plants reported by the Cubeo indigenous village of the Amazon region (Vaupes Medio in Colombia) was evaluated for efficacy against 3D7 (sensitive to chloroquine) and FCR-3 (resistant to chloroquine) Plasmodium falciparum strains. Five percent of these extracts presented a significant antiplasmodial activity (
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed392fa15b333488b486f39ac04042f https://pubmed.ncbi.nlm.nih.gov/27124245 Zobrazit plný text záznamu