Association of Red Blood Cell Distribution Width Levels with Severity of Coronary Artery Disease in Patients with Non-ST Elevation Myocardial Infarction
| Autor: | Huseyin Arinc, Deniz Elcik, Ömer Şahin, Ahmet Oguz Baktir, Serhat Karadavut, Hayrettin Saglam, Mahmut Akpek, Mehmet Gungor Kaya, Goktug Savas, Bahadir Sarli |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Erythrocyte Indices Male medicine.medical_specialty Erythrocytes Turkey Myocardial Infarction Coronary Artery Disease macromolecular substances Risk Assessment Severity of Illness Index Coronary artery disease Electrocardiography Letter to the Editor / Reply Red blood cell distribution width Risk Factors St elevation myocardial infarction Cause of Death Internal medicine Humans Medicine In patient Aged Original Paper business.industry Angiography General Medicine Middle Aged Atherosclerosis medicine.disease SYNTAX score ROC Curve Cardiology Female Non-ST elevation myocardial infarction Emergency Service Hospital business |
| Zdroj: | Medical Principles and Practice |
| ISSN: | 1423-0151 1011-7571 |
| Popis: | Objectives: The aim of this study was to evaluate the association of the levels of red blood cell distribution width (RDW) with the severity of atherosclerosis and to determine whether or not the RDW level on admission is an independent predictor of all-cause mortality in patients with non-ST elevation myocardial infarction (NSTEMI). Materials and Methods: A total of 335 consecutive patients with NSTEMI were enrolled in this study. The patients were divided into high (n = 105) and low (n = 230) SYNTAX groups. The high SYNTAX group was defined as patients with a value in the third tertile (SYNTAX score, SXscore ≥12), while the low SYNTAX group was defined as those with a value in the lower 2 tertiles (SXscore 14.25% and the low RDW group (n = 183) as those with RDW ≤14.25%. All-cause mortality was followed up to 38 months. Results: The mean follow-up period was 18 ± 11 months. The RDW levels of patients were significantly higher in the high SYNTAX group than in the low SYNTAX group (15.2 ± 1.8 vs. 14.2 ± 1.2, p < 0.001). Pearson's coefficients were used to determine the degree of association between RDW levels and SXscore and also between RDW levels and high-sensitivity C-reactive protein. There was a significant correlation between RDW levels and SXscore (r = 0.460, p < 0.001). Also, there was a significant correlation between RDW levels and high-sensitivity C-reactive protein (r = 0.180, p = 0.001). All-cause mortality rate was not significantly different between the high and low RDW groups (log-rank, p = 0.621). Conclusion: RDW levels were independently associated with high SXscore but were not associated with long-term mortality in NSTEMI patients. |
| Databáze: | OpenAIRE |
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