Radial pressure waveform dP/dt max is a poor indicator of left ventricular systolic function
| Autor: | James E. Sharman, Ahmad Qasem, D. S. Gill, Richard Lim, Thomas H. Marwick, L. Hanekom |
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| Rok vydání: | 2007 |
| Předmět: |
Male
Cardiac Catheterization medicine.medical_specialty Cardiac output Systole medicine.medical_treatment Clinical Biochemistry Blood Pressure Biochemistry Ventricular Dysfunction Left Internal medicine medicine.artery medicine Humans Waveform Radial artery Cardiac catheterization business.industry General Medicine Middle Aged Echocardiography Doppler Pulse pressure Blood pressure Radial Artery Cardiology Ventricular pressure Female business |
| Zdroj: | European Journal of Clinical Investigation. 37:276-281 |
| ISSN: | 1365-2362 0014-2972 |
| DOI: | 10.1111/j.1365-2362.2007.01784.x |
| Popis: | The first derivative of left ventricular (LV) pressure over time (dP/dt max) is a marker of LV systolic function that can be assessed during cardiac catheterization and echocardiography. Radial artery dP/dt max has been proposed as a possible marker of LV systolic function and we sought to test this hypothesis.We compared simultaneously recorded radial dP/dt max (by high-fidelity tonometry) with LV dP/dt max (by high-fidelity catheter and echocardiography parameters analogous to LV dP/dt max). In study 1, beat-to-beat radial dP/dt max and LV dP/dt max were recorded at rest and during supine exercise in 12 males (aged 61 +/- 12 years) undergoing cardiac catheterization. In study 2, 2D-echocardiography and radial dP/dt max were recorded in 54 patients (separate to study 1; 39 men; aged 64 +/- 10 years) at baseline and peak dobutamine-induced stress. Three basal septum measures were taken as being analogous to LV dP/dt max: 1. Peak systolic strain rate; 2. Strain rate (SR-dP/dt max) during isovolumic contraction (IVCT) and; 3. Tissue velocity during IVCT.In study 1 there was a significant difference between resting LV dP/dt max (1461 +/- 383 mmHg s(-1)) and radial dP/dt max (1182 +/- 319 mmHg s(-1); P0.001), and a poor, but statistically significant, correlation between the variables (R(2) = 0.006; P0.05). Similar results were observed during exercise. In study 2 there were weak (R(2) = -0.12; P = 0.01) to non-significant associations between radial dP/dt max and all echocardiographic measures analogous to LV dP/dt max at rest or peak stress.Radial pressure waveform dP/dt max is not a reliable marker of LV systolic function. |
| Databáze: | OpenAIRE |
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