Transfer from high-acuity long-term care facilities is associated with carriage of Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae: a multihospital study
| Autor: | Margaret McNally, Sana Ahmed, Ruba Odeh, Andrea Norris, Vishnu Chundi, Robert A. Weinstein, Kavitha Prabaker, Michael Y. Lin, Kartikeya Cherabuddi, Mary K. Hayden, Karen Lolans |
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| Rok vydání: | 2012 |
| Předmět: |
Microbiology (medical)
Male Pediatrics medicine.medical_specialty Carbapenemase-Producing Enterobacteriaceae Epidemiology Klebsiella pneumoniae beta-Lactamases Article Bacterial Proteins Internal medicine Acute care Drug Resistance Bacterial medicine Confidence Intervals Escherichia coli Odds Ratio Prevalence Humans Risk factor Propensity Score Escherichia coli Infections Aged Skilled Nursing Facilities Aged 80 and over Chicago Cross Infection biology business.industry Rectum Odds ratio Middle Aged biology.organism_classification Respiration Artificial Care facility Klebsiella Infections Community-Acquired Infections Long-term care Infectious Diseases Carriage Carbapenems Case-Control Studies Carrier State Female business Multilocus Sequence Typing |
| Zdroj: | Infect Control Hosp Epidemiol |
| ISSN: | 1559-6834 0195-9417 |
| Popis: | Objective.To determine whether transfer from a long-term care facility (LTCF) is a risk factor for colonization with Klebsiella pneumoniae carbapenemase (KPC)–producing Enterobacteriaceae upon acute care hospital admission.Design.Microbiologic survey and nested case-control study.Setting.Four hospitals in a metropolitan area (Chicago) with an early KPC epidemic.Patients.Hospitalized adults.Methods.Patients transferred from LTCFs were matched 1 : 1 to patients admitted from the community by age (± 10 years), admitting clinical service, and admission date (± 2 weeks). Rectal swab specimens were collected within 3 days after admission and tested for KPC-producing Enterobacteriaceae. Demographic and clinical information was extracted from medical records.Results.One hundred eighty patients from LTCFs were matched to 180 community patients. KPC-producing Enterobacteriaceae colonization was detected in 15 (8.3%) of the LTCF patients and 0 (0%) of the community patients (PPP = .022) with KPC-producing Enterobacteriaceae than patients from an SNF.Conclusions.Patients admitted to acute care hospitals from high-acuity LTCFs (ie, VSNFs and LTACHs) were more likely to be colonized with KPC-producing Enterobacteriaceae than were patients admitted from the community. Identification of healthcare facilities with a high prevalence of colonized patients presents an opportunity for focused interventions that may aid regional control efforts. |
| Databáze: | OpenAIRE |
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