Enantioselective Ni-Al Bimetallic Catalyzed exo-Selective C-H Cyclization of Imidazoles with Alkenes

Autor:	Shan Wang, Yin-Xia Wang, Xingwang Han, Hao Chen, Shao-Long Qi, Mengchun Ye, Yu-Xin Luan
Rok vydání:	2018
Předmět:	010405 organic chemistry Chemistry Enantioselective synthesis General Chemistry 010402 general chemistry 01 natural sciences Biochemistry Catalysis 0104 chemical sciences chemistry.chemical_compound Colloid and Surface Chemistry Yield (chemistry) Organic chemistry Bifunctional Bimetallic strip
Zdroj:	Journal of the American Chemical Society. 140(16)
ISSN:	1520-5126
Popis:	A Ni–Al bimetallic catalyzed enantioselective C–H exo-selective cyclization of imidazoles with alkenes has been developed. A series of bi- or polycyclic imidazoles with β-stereocenter were obtained in up to 98% yield and >99% ee. The bifunctional SPO ligand-promoted bimetallic catalysis proved to be critical to this challenging stereocontrol.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2eadc05c22845e5b892cbef8f82559 https://pubmed.ncbi.nlm.nih.gov/29641189 Zobrazit plný text záznamu