Computer-assisted comparative analysis of four-sector and six-sector biopsies of the prostate
| Autor: | Michel Bazinet, Armen Aprikian, Pierre I. Karakiewicz, Alaa W. Meshref |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty Biopsy Urology Asymptomatic Random Allocation Prostate cancer Prostate medicine Humans Diagnosis Computer-Assisted Prospective Studies Aged medicine.diagnostic_test business.industry Prostatic Neoplasms Cancer medicine.disease Surgery Numero sign medicine.anatomical_structure Potential difference Adenocarcinoma Radiology medicine.symptom business |
| Zdroj: | Urology. 48:747-750 |
| ISSN: | 0090-4295 |
| DOI: | 10.1016/s0090-4295(96)00230-0 |
| Popis: | Objectives To assess the potential difference in positive biopsy rates between four-sector and six-sector biopsy methods. Methods This computer-assisted analysis is based on the records of 156 consecutive patients previously diagnosed with T1c cancer on systematic sextant biopsy of the peripheral zone. For each patient the computer randomly deleted one biopsy result from the left and right prostatic lobes. The deletion process was repeated 1000 times. Based on four randomly chosen biopsy cores, we determined the number of undetected cancers initially diagnosed with sextant biopsy. Results Based on four-sector biopsy cores of the peripheral zone, between 6 and 30 (3.8% to 19.2% of cases) nonpalpable, isoechoic prostate cancers that were detected with sextant biopsy would have remained undiagnosed. Conclusions Our results suggest that the number of biopsy cores used in the early detection of nonpalpable, isoechoic prostate cancer may substantially affect the rate of positive findings. |
| Databáze: | OpenAIRE |
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