Successful percutaneous CT-guided microwave ablation of adrenal gland for ectopic Cushing syndrome
| Autor: | Rebecca Zener, Amol Mujoomdar, D Gray, Stan Van Uum, Andrew Zaleski |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Ablation Techniques
Pathology medicine.medical_specialty medicine.drug_class Adrenal Gland Neoplasm Adrenal Gland Neoplasms Adrenocorticotropic hormone 030218 nuclear medicine & medical imaging 03 medical and health sciences Cushing syndrome 0302 clinical medicine Adrenal Glands Adrenal insufficiency medicine Humans Radiology Nuclear Medicine and imaging Microwaves Cushing Syndrome business.industry Adrenal gland Microwave ablation Middle Aged medicine.disease Pancreatic Neoplasms Neuroendocrine Tumors Treatment Outcome medicine.anatomical_structure Mineralocorticoid 030220 oncology & carcinogenesis Female Tomography X-Ray Computed business Glucocorticoid medicine.drug |
| Zdroj: | Clinical Imaging. 42:93-95 |
| ISSN: | 0899-7071 |
| DOI: | 10.1016/j.clinimag.2016.11.021 |
| Popis: | Adrenocorticotropic hormone production by pancreatic neuroendocrine tumor (PNET) is rare and results in hyperstimulation of the adrenal gland to produce ectopic Cushing syndrome. Our case showcases the safety and effectiveness of percutaneous CT-guided microwave ablation of the adrenal gland in a 49-year-old female with PNET and hepatic metastases who presented with ectopic Cushing syndrome despite surgical resection of the primary pancreatic tumor and left adrenal gland. Prior to ablation, the right adrenal gland measured 4.3×1.6×2.0cm and the patient had malignant hypertension with elevated morning serum cortisol level (1976nmol/L). After microwave ablation of the right adrenal gland, the hypertension resolved and the cortisol level decreased dramatically (74nmol/L). As expected after successful treatment, the patient developed adrenal insufficiency and was placed on glucocorticoid and mineralocorticoid supplementation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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