Botulinum Toxin A in the Treatment of Chromhidrosis
| Autor: | Jessie M Wu, Adam J. Mamelak, Rachel Nussbaum, Patrick S J McElgunn |
|---|---|
| Rok vydání: | 2006 |
| Předmět: |
Adult
medicine.medical_specialty Pathology Botulinum Toxins Stimulation Substance P Dermatology SWEAT Diagnosis Differential chemistry.chemical_compound Therapeutic approach Recurrence medicine Sweat Gland Diseases Humans Chromhidrosis business.industry Apocrine General Medicine medicine.disease Axilla medicine.anatomical_structure Cheek chemistry Neuromuscular Agents Cholinergic Female Surgery business Pigmentation Disorders |
| Zdroj: | Dermatologic Surgery. 31:963-965 |
| ISSN: | 1076-0512 |
| DOI: | 10.1111/j.1524-4725.2005.31814 |
| Popis: | Background. Chromhidrosis is an uncommon disorder characterized by secretion of colored sweat by apocrine glands, typically localized to the face or axilla. The current treatments available for chromhidrosis are time consuming and frequently ineffective. Objective. Our purpose is to demonstrate a novel approach to the treatment of apocrine chromhidrosis. Methods. We report a case of apocrine chromhidrosis successfully treated with botulinum toxin A (BTX-A; Botox). Results. BTX-A therapy successfully controlled facial chromhidrosis, and the effects were visible at 19 weeks post-treatment. The therapeutic benefits may be attributed to its inhibitory effects on cholinergic stimulation, adrenergic stimulation, and substance P release, although further studies are necessary to elucidate the precise mechanism of action. Conclusion. This report demonstrates a new therapeutic approach to patients suffering from chromhidrosis. |
| Databáze: | OpenAIRE |
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