Cephalexin dosage in general practice assessed by double-blind trial
| Autor: | Susan E. Johnson, R. D. Foord |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Adolescent Dose Gastrointestinal Diseases Urinary system Administration Oral Infections Placebo Drug Hypersensitivity Double blind Humans Medicine Sinusitis Bronchitis Vaginitis Oral therapy Aged Cephalexin Clinical Trials as Topic Stomatitis Adult patients business.industry General Medicine Middle Aged Otitis Externa Otitis Media Tooth Diseases Urinary Tract Infections General practice Female Nervous System Diseases Family Practice business |
| Zdroj: | Current Medical Research and Opinion. 1:37-48 |
| ISSN: | 1473-4877 0300-7995 |
| DOI: | 10.1185/03007997209111143 |
| Popis: | SummaryIn a double-blind multicentre trial conducted in general practice, 851 adult patients were treated with either cephalexin (‘Ceporex’) tablets 250 mg. or 500 mg. q.d.s. for 7 days. The trial included the common infections, excepting pneumonias and sore throats, of general practice which were suitable for oral therapy. Ethical considerations did not allow inclusion of a control group treated with a placebo. The patients were assessed clinically, but for those with urinary tract infections the bacteriological response was also investigated. In each of the types of infections both dosages were equally effective. Irrespective of dosage, 90% of the whole group of patients improved by the third day, the response rates at the end of treatment were similar (87%) and the incidences of adverse reactions were not significantly different (11.5 % with 1 g./day and 10% with 2 g./day). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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