Randomized clinical trial of the efficacy of trial-based cognitive therapy for obsessive-compulsive disorder: Preliminary findings

Autor: Eleonardo Pereira, Rodrigues, Ana Jardel Batista, Fechine, Antonio César, Oliveira, Cristiane Francisca Ferreira, Matos, Cristiane de Medeiros, Passarela, Curt, Hemanny, Francimeuda de Morais, Dias, José Wilson, Batista, Luciana Nogueira, Albuquerque, Myrla Sirqueira, Soares, Pedro Evangelista, Coelho, Vanessa Pires, Araújo, Zila Mendes, Ayres, Irismar Reis de, Oliveira
Rok vydání: 2022
Předmět:
Zdroj: Trends in Psychiatry and Psychotherapy.
ISSN: 2238-0019
2237-6089
Popis: Obsessive-compulsive disorder (OCD) is the fourth most prevalent and disabling mental disorder. OCD is associated with anatomical and functional changes in the brain, in addition to dysfunctional cognitions. Selective serotonin reuptake inhibitors (SSRIs), cognitive-behavioral therapy (CBT), and exposure and response prevention (ERP) are the treatments of choice. Trial-based cognitive therapy (TBCT) is a recent and empirically validated psychotherapy with a focus on restructuring the dysfunctional negative core beliefs (CBs). The objective of this study was to evaluate the TBCT efficacy relative to ERP in the OCD treatment.A randomized, single-blind clinical trial was conducted, randomizing 26 patients for individual treatment with TBCT (n = 12) or ERP (n = 14). The groups were evaluated at baseline, at the end of 3 months (12 sessions) and at 3-, 6- and 12-month follow-up.Both approaches reduced the severity of symptoms with large effect sizes. These results were maintained in the 12-month follow-up assessment.TBCT may be a valid and promising treatment for this disorder.
Databáze: OpenAIRE