Efficient Synthesis of 3,3′-Mixed Bisindoles via Lewis Acid Catalyzed Reaction of Spiro-epoxyoxindoles and Indoles

Autor:	Ramkrishna Maity, Subrata Maity, Saumen Hajra
Rok vydání:	2015
Předmět:	Indoles Molecular Structure Chemistry Organic Chemistry Regioselectivity Total synthesis Ring (chemistry) Biochemistry Catalysis Piperazines Pyrrolidinones Oxindoles Molecule Organic chemistry Spiro Compounds Lewis acids and bases Physical and Theoretical Chemistry Lewis Acids
Zdroj:	Organic Letters. 17:3430-3433
ISSN:	1523-7052 1523-7060
DOI:	10.1021/acs.orglett.5b01432
Popis:	An efficient strategy for the synthesis of 3-(3-indolyl)-oxindole-3-methanol has been developed to achieve a Lewis acid catalyzed, highly regioselective ring opening of spiro-epoxyoxindoles with indoles. The method is used for the gram-scale formal total synthesis of (±)-gliocladin C.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed450a82f4fd1d529ccb458e1d8fe9a6 https://doi.org/10.1021/acs.orglett.5b01432 Zobrazit plný text záznamu