Splenic hemangioma with thrombocytopenia and afibrinogenemia
| Autor: | Dallas V. Clatanoff, L. Gilbert Thatcher, E. Richard Stiehm |
|---|---|
| Rok vydání: | 1968 |
| Předmět: |
Male
medicine.medical_specialty Anemia medicine.medical_treatment Fibrinogen Hemangioma hemic and lymphatic diseases Fibrinolysis Humans Medicine Splenic Hemangioma Splenic Diseases Radioisotopes Factor VIII Afibrinogenemia business.industry Factor V Infant Hypofibrinogenemia medicine.disease Thrombocytopenia Abdominal mass Surgery Pediatrics Perinatology and Child Health Splenectomy Blood Coagulation Tests medicine.symptom business medicine.drug |
| Zdroj: | The Journal of Pediatrics. 73:345-354 |
| ISSN: | 0022-3476 |
| DOI: | 10.1016/s0022-3476(68)80111-8 |
| Popis: | A 16-month-old boy who presented with bruising, anemia, an abdominal mass, thrombocytopenia, and afibrinogenemia was cured by the surgical removal of a large splenic hemangioma. Preoperatively, coagulation studies revealed low normal levels of Factors V and VIII, normal fibrinolysis, and high levels of immunologically detectable split products of fibrinogen. The half-life of 131 I-labeled fibrinogen was 36 hours preoperatively and 72 hours postoperatively. Thirteen other cases of hemangioma and thrombocytopenia (Kasabach-Merritt syndrome) associated with hypofibrinogenemia are reviewed. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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