Application of a leukocyte and nitrite urine test strip to the management of children with neurogenic bladder

Autor: G. Keith Chambers, John D. Anderson, Hjalmar W. Johnson
Rok vydání: 1993
Předmět:
Zdroj: Diagnostic Microbiology and Infectious Disease. 17:29-33
ISSN: 0732-8893
DOI: 10.1016/0732-8893(93)90066-g
Popis: A urine leukocyte count ofor = 50/mm3 together with a bacterial count ofor = 10(5) colony-forming units (CFUs) per milliliter was used to define significant infection in 160 children with neurogenic bladder and evaluate the leukocyte and nitrite components of the Chemstrip 9 test. A Chemstrip 9 leukocyte reading ofor = 25 together with a negative nitrite reaction occurred in 99 children and had a sensitivity of 83.5% and a negative predictive value for infection of 97.0%. A Chemstrip 9 reading ofor = 500 leukocytes together with a positive nitrite reaction occurred in 18 children and had a sensitivity of 40% with a 100% positive predictive value for infection. Other combinations of Chemstrip 9 leukocyte and nitrite reactions were unhelpful or of uncertain value. Selection of up to three specimens from each patient increased the number of samples to 360 and provided general confirmation of the above conclusions. Nitrofurantoin may reduce the sensitivity of the nitrite strip reaction.
Databáze: OpenAIRE