Initial outcomes with image‐guided partial breast irradiation delivered with intensity‐modulated radiation therapy
| Autor: | Bindu V. Manyam, Elizabeth Obi, Sheen Cherian, Stephen R. Grobmyer, Martin C. Tom, Jame Abraham, Chirag Shah, Ping Xia, Betty B. Obi, Rahul D. Tendulkar, Zahraa Al-Hilli, Eric Murray |
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| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Every other day Breast Neoplasms Mastectomy Segmental 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Breast cancer Internal Medicine medicine Humans Fat necrosis Single institution Radiation Injuries Chronic toxicity Aged business.industry Partial Breast Irradiation Middle Aged Intensity-modulated radiation therapy medicine.disease Oncology 030220 oncology & carcinogenesis Female Radiotherapy Adjuvant Surgery Dose Fractionation Radiation Radiotherapy Intensity-Modulated Radiology business |
| Zdroj: | The Breast Journal. 26:227-230 |
| ISSN: | 1524-4741 1075-122X |
| DOI: | 10.1111/tbj.13544 |
| Popis: | Patients were treated at a single institution to a dose of 30 Gy in five fractions delivered every other day using image-guided intensity modulated radiation therapy (IMRT) partial breast irradiation. A total of 34 patients were treated with a median follow-up of 4.6 months. The rate of acute Grade 1 dermatitis was 23.5% (n = 8), and Grade 1 fatigue was 17.6% (n = 6), with no Grade 2 or higher acute toxicities. The rate of chronic Grade 1 dermatitis was 25.0% (n = 6), Grade 1 fat necrosis 4.2% (n=1), with no patients demonstrating other chronic toxicities. Image-guided APBI delivered with IMRT is associated with low rates of acute and chronic toxicity though additional follow-up is warranted. |
| Databáze: | OpenAIRE |
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