Reversible atransferrinemia in a patient with chronic enteropathy: is transferrin mandatory for iron transport?

Autor: Hana Manceau, Katell Peoc’h, Hervé Puy, Arnaud Bruneel, Alexandre Raynor, Carmen Stefanescu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Biochemia Medica
Volume 33
Issue 1
ISSN: 1846-7482
1330-0962
Popis: Herein, we report the case of a 42-year-old woman, hospitalized in a French tertiary hospital for a relapse of a chronic enteropathy, who was found on admission to have no detectable serum transferrin. Surprisingly, she only exhibited mild anaemia. This atransferrinemia persisted for two months throughout her hospitalization, during which her haemoglobin concentration remained broadly stable. Based on her clinical history and evolution, we concluded to an acquired atransferrinemia secondary to chronic undernutrition, inflammation and liver failure. We discuss the investigations performed in this patient, and hypotheses regarding the relative stability of her haemoglobin concentration despite the absence of detectable transferrin.
Databáze: OpenAIRE