Laparoscopic vs. open abdominal surgery in male pigs: Marked differences in cortisol and catecholamine response depending on the size of surgical incision

Autor: Panagiotis E. Karayannacos, Emmanouil Zoumakis, Evangelos Balafas, Gregory Skalkeas, George P. Chrousos, Gregory Kouraklis, Angeliki Krikri, Vasileios Alexopoulos, Paraskevas Katsaronis
Rok vydání: 2013
Předmět:
Zdroj: HORMONES. 12:283-291
ISSN: 1109-3099
DOI: 10.14310/horm.2002.1412
Popis: OBJECTIVE: Minimally invasive operations, such as laparoscopic cholecystectomy and adrenalectomy, result in a more rapid recovery of normal function, less physiological disturbances and less stress to the organism than similar open operations. The purpose of this study was to determine the stress response associated with minimally invasive abdominal surgery compared to conventional small or large incision laparotomy. METHODS: We compared the responses of the stress hormones cortisol and the catecholamines adrenaline and noradrenaline to elective conventional and laparoscopic cholecystectomy and unilateral adrenalectomy in male pigs. Blood samples were taken from all animals at the same time, one day before surgery, at the beginning of the operation, every 15 minutes during surgery and on the first postoperative morning. RESULTS: Plasma adrenaline and noradrenaline concentrations were significantly lower in both cholecystectomies (p
Databáze: OpenAIRE