Intra-saccular device modeling for treatment planning of intracranial aneurysms: from morphology to hemodynamics
| Autor: | Ignacio Larrabide, Hector Fernandez, Romina Muñoz, Ana Paula Narata, Nicolás Ignacio Dazeo |
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| Rok vydání: | 2021 |
| Předmět: |
Computer science
0206 medical engineering Biomedical Engineering Health Informatics 02 engineering and technology Computational fluid dynamics 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Aneurysm medicine Shear stress Humans Computer Simulation Radiology Nuclear Medicine and imaging Radiation treatment planning Lead (electronics) Bifurcation business.industry Hemodynamics Models Cardiovascular Intracranial Aneurysm General Medicine Blood flow medicine.disease 020601 biomedical engineering Computer Graphics and Computer-Aided Design Computer Science Applications Surgery Stress Mechanical Computer Vision and Pattern Recognition Porous medium business Biomedical engineering |
| Zdroj: | International Journal of Computer Assisted Radiology and Surgery. 16:1663-1673 |
| ISSN: | 1861-6429 1861-6410 |
| DOI: | 10.1007/s11548-021-02427-9 |
| Popis: | Intra-saccular devices (ID), developed for the treatment of bifurcation aneurysms, offer new alternatives for treating complex terminal and bifurcation aneurysms. In this work, a complete workflow going from medical images to post-treatment CFD analysis is described and used in the assessment of a concrete clinical problem. Two different intra-saccular device sizes were virtually implanted in 3D models of the patient vasculature using the ID-Fit method. After deployment, the local porosity at the closed end of the device in contact with the blood flow was computed. This porosity was then used to produce a CFD porous medium model of the device. Velocities and wall shear stress were assessed for each model. Six patients treated with intra-saccular devices were included in this work. For each case, 2 different device sizes were virtually implanted and 3 CFD simulations were performed: after deployment simulation with each size and before deployment simulation (untreated). A visible reduction in velocities was observed after device implantation. Velocity and WSS reduction was statistically significant (K–S statistics, $$p |
| Databáze: | OpenAIRE |
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