Intra-arterial chemotherapy for liver metastases
Autor: | Nancy E. Kemeny, Louise Catherine Connell |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
Colorectal cancer medicine.medical_treatment Disease Gastroenterology Article Resection 03 medical and health sciences 0302 clinical medicine Hepatic arterial infusion Hepatic Artery Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Hepatectomy Humans Infusions Intra-Arterial Intrahepatic Cholangiocarcinoma Chemotherapy business.industry Incidence (epidemiology) Liver Neoplasms medicine.disease digestive system diseases Intraarterial chemotherapy Oncology 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Surgery Fluorouracil business Colorectal Neoplasms |
Zdroj: | Surg Oncol Clin N Am |
Popis: | Colorectal cancer (CRC) is one of the leading cancers globally in terms of both incidence and cancer-related mortality. Liver metastatic disease is the main prognostic driver for patients with CRC. The management options for liver metastatic CRC continue to evolve, particularly with the incorporation of locoregional therapies into the treatment paradigm. Hepatic arterial infusion (HAI) chemotherapy is one such liver directed approach used with the goal of converting patients to liver resection, reducing the risk of recurrence, treating recurrent disease, and most importantly improving overall survival. This article summarizes the role of HAI chemotherapy in the treatment of liver metastatic CRC. |
Databáze: | OpenAIRE |
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