Guanacastepene-A total synthesis: construction of the tricyclic iso-guanacastepane, epi-guanacastepane and guanacastepane frameworks

Autor:	Goverdhan Mehta, Kalidindi Srinivas, Jayant D. Umarye
Rok vydání:	2003
Předmět:	chemistry.chemical_classification chemistry.chemical_compound chemistry Organic Chemistry Drug Discovery Organic chemistry Total synthesis Guanacastepene A Diterpene Biochemistry Combinatorial chemistry Tricyclic
Zdroj:	Tetrahedron Letters. 44:4233-4237
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(03)00883-9
Popis:	Studies aimed towards the total synthesis of the diterpene antibiotic, guanacastepene A, of current interest and displaying promising biological activity against drug resistant pathogens has led to the generation of some novel tricyclic skeleta replete with extensive functionalization and representing interesting variations of the guanacastepane framework.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea8557c01b9489c3eef9b1c92919f966 https://doi.org/10.1016/s0040-4039(03)00883-9 Zobrazit plný text záznamu Full Text from ScienceDirect