Electroacupuncture induces antihyperalgesic effect through endothelin-B receptor in the chronic phase of a mouse model of complex regional pain syndrome type I

Autor: Leidiane Mazzardo-Martins, Daniel Martins, Daniela Dero Ludtke, Daiana Cristina Salm, Verônica Vargas Horewicz, Elisa C. Winkelmann-Duarte, Anna Paula Piovezan, Ari Ojeda Ocampo Moré, Luiz Augusto Oliveira Belmonte, Júlia Koerich Ferreira, Kamilla Pamplona Frech, Francisco José Cidral-Filho
Rok vydání: 2018
Předmět:
Zdroj: Pflugers Archiv : European journal of physiology. 470(12)
ISSN: 1432-2013
Popis: Complex regional pain syndrome (CRPS) is a disorder that involves abnormal inflammation and nerve dysfunction frequently resistant to a broad range of treatments. Peripheral nerve stimulation with electroacupuncture (EA) has been widely used in different clinical conditions to control pain and inflammation; however, the use of EA in the treatment of CRPS is under investigation. In this study, we explore the effects of EA on hyperalgesia and edema induced in an animal model of chronic post-ischemia pain (CPIP model) and the possible involvement of endothelin receptor type B (ET
Databáze: OpenAIRE