Maternal electronic cigarette use during pregnancy affects long-term arterial function in offspring

Autor:	Eiman Aboaziza, Kimberly Feaster, Lance Hare, Paul D. Chantler, I. Mark Olfert
Rok vydání:	2023
Předmět:	Aerosols Nicotine Physiology Vaping Parturition Arteries Electronic Nicotine Delivery Systems Pulse Wave Analysis Rats Rats Sprague-Dawley Pregnancy Physiology (medical) Animals Humans Female
Zdroj:	Journal of Applied Physiology. 134:59-71
ISSN:	1522-1601 8750-7587
DOI:	10.1152/japplphysiol.00582.2022
Popis:	Vaping, or electronic cigarette (ecig) use, is prevalent among pregnant women, although little is known about the effects of perinatal ecig use on cardiovascular health of the progeny (even when using nicotine-free e-liquid). Maternal toxicant inhalation may adversely affect vital conduit vessel development. We tested the hypothesis that perinatal exposure to maternal vaping would lead to a dose-dependent dysfunction that would persist into later life of offspring. Pregnant Sprague-Dawley rats were exposed to either nicotine-free (ecig0) or nicotine-containing ecig aerosol (18 mg/mL, ecig18) starting on
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea50a0b887ea33c5a1d40d164a933c7a https://doi.org/10.1152/japplphysiol.00582.2022 Zobrazit plný text záznamu