Long-acting ACE inhibitor-induced angioedema
| Autor: | Christine L. Holland, Leonard Bielory, Sylvia Lee, Michael Jaker |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty medicine.medical_treatment Angiotensin-Converting Enzyme Inhibitors Gastroenterology Enalapril immune system diseases Lisinopril Internal medicine Immunology and Allergy Medicine Intubation Humans cardiovascular diseases Angioedema skin and connective tissue diseases Adverse effect Aged Aged 80 and over biology business.industry food and beverages Captopril Angiotensin-converting enzyme General Medicine Middle Aged ACE inhibitor biology.protein Female medicine.symptom business Respiratory Insufficiency circulatory and respiratory physiology medicine.drug |
| Zdroj: | Allergy proceedings : the official journal of regional and state allergy societies. 13(2) |
| ISSN: | 1046-9354 |
| Popis: | Angioedema is a known adverse reaction of the angiotensin converting enzyme (ACE) inhibitors. Although current investigations are in progress, the exact pathogenesis of ACE inhibitor-induced angioedema is still unclear. Most cases of angioedema we have seen remitting from the short-acting ACE inhibitor, captopril, have presented with mild angioedema, controlled with antihistamines and glucocorticosteroids. In contrast, the angioedema induced by the long-acting ACE inhibitors have been serious. Our five patients developed angioedema from either lisinopril or enalapril. Three of five patients presented with severe angioedema requiring intubation, and one of these patients had a tracheostomy. One patient with a history of mild angioedema secondary to captopril subsequently required intubation for his enalapril-induced angioedema. |
| Databáze: | OpenAIRE |
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