Heat shock protein 90 inhibition in the inflamed lungs
| Autor: | Nektarios Barabutis |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Inflammation Respiratory Distress Syndrome business.industry Acute Lung Injury Anti-Inflammatory Agents Cell Biology Acute respiratory distress Biochemistry Cell Line 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Heat shock protein Immunology Medicine Animals Humans HSP90 Heat-Shock Proteins medicine.symptom Perspective and Reflection Article business Lung |
| Zdroj: | Cell Stress Chaperones |
| ISSN: | 1466-1268 |
| Popis: | Heat shock protein 90 is a highly conserved molecular chaperone, essential for cellular survival under diverse environments. Since this protein is employed by tumors to promote their prevalence, heat shock protein 90 inhibitors have been developed to oppose malignancies. The anti-cancer effects of those compounds appear to be associated with anti-inflammatory properties. Thus, ongoing laborious efforts investigate the possible application of those agents towards inflammatory disorders of the lungs, such as the acute respiratory distress syndrome. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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