| Autor: |
M.M. Schreuder, S. Hamkour, K.E. Siegers, K.B. Holven, A.K. Johansen, M.A. van de Ree, B. Imholz, E. Boersma, L. Louters, M.P. Bogsrud, K. Retterstøl, F.L.J. Visseren, J.E. Roeters van Lennep, C. Koopal |
| Přispěvatelé: |
Internal Medicine, Cardiology |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Atherosclerosis. Elsevier Ireland Ltd |
| ISSN: |
0021-9150 |
| Popis: |
Background and aims: Despite lipid lowering therapy (LLT), reaching LDL-C targets in patients with familial hypercholesterolemia (FH) remains challenging. Our aim was to determine attainment of LDL-C target levels and reasons for not reaching these in female and male FH patients. Methods: We performed a cross-sectional study of heterozygous FH patients in five hospitals in the Netherlands and Norway. Clinical characteristics and information about LLT, lipid levels and reasons for not being on LDL-C treatment target were retrospectively collected from electronic medical records. Results: We studied 3178 FH patients (53.9% women), median age 48.0 (IQR 34.0–59.9) years. Median LDL-C before treatment and on-treatment was higher in women compared to men (6.2 (IQR 5.1–7.3) and 6.0 (IQR 4.9–7.2) mmol/l (p=0.005) and 3.0 (IQR 2.4–3.8) and 2.8 (IQR 2.3–3.5) mmol/L (p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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