Utilization of focal therapy for patients discontinuing active surveillance of prostate cancer: Recommendations of an international Delphi consensus
| Autor: | Wei Phin Tan, Ardeshir R. Rastinehad, Laurence Klotz, Peter R. Carroll, Mark Emberton, John F. Feller, Arvin K. George, Inderbir S. Gill, Rajan T. Gupta, Aaron E. Katz, Amir H. Lebastchi, Leonard S. Marks, Giancarlo Marra, Peter A. Pinto, Daniel Y. Song, Abhinav Sidana, John F. Ward, Rafael Sanchez-Salas, Jean de la Rosette, Thomas J Polascik, Aaron Katz, Alireza Aminsharifi, Amir Lebastchi, Andre Abreu, Arnauld Villers, Ariel Schulman, Ardeshir Rastinehad, Arvin George, Aytekin Oto, Baris Turkbey, Bernard Malavaud, Berrend Muller, Caroline Moore, Daniel Eberli, Daniel Margolis, Daniel Song, Derek Lomas, Hazem Orabi, Herbert Lepor, Hui Meng Tan, Ivan Jambor, Jeremy Grummet, John Feller, John Ward, Jonathan Colemen, Justin Gregg, Kae Jack Tay, Leonard Marks, Leslie Deane, M. Pilar Laguna, Masaki Kimura, Matvey Tsivian, Michael Gorin, Minhaj Siddiqui, Osamu Ukimura, Paolo Gontero, Peter Carroll, Peter Pinto, Pierre Mozer, Rajan T Gupta, Ro Arcot, Samir Taneja, Sangeet Ghai, Sebastian Crouzet, Sherif Mehralivand, Steven Joniau, Sunao Shoji, Takumi Shiraishi, Thomas Polascik, Toshitaka Shin, Uri Lindnet, Varaha Tammisetti, Willemien van den Bos, Yoh Matsuoka |
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| Přispěvatelé: | University of Zurich, Polascik, Thomas J |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Ablation Techniques
Male Delphi Technique 030232 urology & nephrology Active surveillance Prostate cancer 0302 clinical medicine 80 and over computer.programming_language Cancer Aged 80 and over Prostate Cancer Urology & Nephrology Middle Aged Oncology 030220 oncology & carcinogenesis Respondent 2730 Oncology 2748 Urology Urologic Diseases medicine.medical_specialty Consensus Urology Oncology and Carcinogenesis Partial gland ablation Active surveillance of prostate cancer 610 Medicine & health Article Focal Therapy Group Authors 03 medical and health sciences Clinical Research Focal therapy Radiation oncology medicine Humans Radical therapy Watchful Waiting Aged Localized prostate cancer business.industry Prostatic Neoplasms medicine.disease 10062 Urological Clinic Family medicine Imaging technology business computer Delphi |
| Zdroj: | Urol Oncol Urologic oncology, vol 39, iss 11 |
| Popis: | Background: With the advancement of imaging technology, focal therapy (FT) has been gaining acceptance for the treatment of select patients with localized prostate cancer (CaP). We aim to provide details of a formal physician consensus on the utilization of FT for patients with CaP who are discontinuing active surveillance (AS). Methods: A 3-stage Delphi consensus on CaP and FT was conducted. Consensus was defined as agreement by >= 80% of physicians. An in-person meeting was attended by 17 panelists to formulate the consensus statement. Results: Fifty-six respondents participated in this interdisciplinary consensus study (82% urologist, 16% radiologist, 2% radiation oncology). The participants confirmed that there is a role for FT in men discontinuing AS (48% strongly agree, 39% agree). The benefit of FT over radical therapy for men coming off AS is: less invasive (91%), has a greater likelihood to preserve erectile function (91%), has a greater likelihood to preserve urinary continence (91%), has fewer side effects (86%), and has early recovery post-treatment (80%). Patients will need to undergo mpMRI of the prostate and/or a saturation biopsy to determine if they are potential candidates for FT. Our limitations include respondent's biases and that the participants of this consensus may not represent the larger medical community. Conclusions: FT can be offered to men coming off AS between the age of 60 to 80 with grade group 2 localized cancer. This consensus from a multidisciplinary, multi-institutional, international expert panel provides a contemporary insight utilizing FT for CaP in select patients who are discontinuing AS. United States Department of Health & Human Services National Institutes of Health (NIH) - USA ; European Urological Scholarship Programme (EUSP) |
| Databáze: | OpenAIRE |
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