TriTrypDB: a functional genomic resource for the Trypanosomatidae
Autor: | Isabelle Phan, Jessica C. Kissinger, Cary Pennington, Ganesh Srinivasamoorthy, Matthew Berriman, Peter J. Myler, Siddhartha Mitra, Gowthaman Ramasamy, Brian P. Brunk, Haiming Wang, John A. Miller, John Brestelli, Bindu Gajria, Eileen Kraemer, Xin Gao, Christian J. Stoeckert, Frank Innamorato, Charles Treatman, Adrian Tivey, Mark Carrington, David S. Roos, Wei Li, Matthew B. Rogers, John Iodice, Martin Aslett, Sandhya Subramanian, Malcolm J. Gardner, Dhileep Sivam, Gregory R. Grant, Daniel P. Depledge, Giles S. Velarde, Deborah F. Pinney, Cristina Aurrecoechea, Omar S. Harb, Deborah F. Smith, Steve Fischer, Alan R. Gingle, Christopher A. Ross, Ryan Thibodeau, Mark Heiges, Vishal Nayak, Robin Houston, Christiane Hertz-Fowler, Flora J. Logan |
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Rok vydání: | 2009 |
Předmět: |
Trypanosoma
030231 tropical medicine Protozoan Proteins Information Storage and Retrieval Genomics Context (language use) Computational biology Biology Genome 03 medical and health sciences Annotation User-Computer Interface 0302 clinical medicine Resource (project management) Databases Genetic Genetics Animals Databases Protein 030304 developmental biology Leishmania 0303 health sciences Internet Full text search Computational Biology Genome project Articles Protein Structure Tertiary Databases Nucleic Acid Functional genomics Genome Protozoan Software |
Zdroj: | Nucleic Acids Research |
ISSN: | 1362-4962 |
Popis: | TriTrypDB (http://tritrypdb.org) is an integrated database providing access to genome-scale datasets for kinetoplastid parasites, and supporting a variety of complex queries driven by research and development needs. TriTrypDB is a collaborative project, utilizing the GUS/WDK computational infrastructure developed by the Eukaryotic Pathogen Bioinformatics Resource Center (EuPathDB.org) to integrate genome annotation and analyses from GeneDB and elsewhere with a wide variety of functional genomics datasets made available by members of the global research community, often pre-publication. Currently, TriTrypDB integrates datasets from Leishmania braziliensis, L. infantum, L. major, L. tarentolae, Trypanosoma brucei and T. cruzi. Users may examine individual genes or chromosomal spans in their genomic context, including syntenic alignments with other kinetoplastid organisms. Data within TriTrypDB can be interrogated utilizing a sophisticated search strategy system that enables a user to construct complex queries combining multiple data types. All search strategies are stored, allowing future access and integrated searches. 'User Comments' may be added to any gene page, enhancing available annotation; such comments become immediately searchable via the text search, and are forwarded to curators for incorporation into the reference annotation when appropriate. |
Databáze: | OpenAIRE |
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