Mean Platelet Volume as a Potential Predictor of Cholesteatoma in Children
| Autor: | Serhan Derin, Mehmet Akif Eryilmaz |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Adolescent Hearing loss Independent predictor Gastroenterology 03 medical and health sciences 0302 clinical medicine Predictive Value of Tests Internal medicine medicine Humans In patient Mean platelet volume Child Cholesteatoma 030223 otorhinolaryngology Retrospective Studies Platelet lymphocyte ratio Cholesteatoma Middle Ear business.industry Curve analysis General Medicine medicine.disease Predictive value Otorhinolaryngology Female Surgery medicine.symptom business Mean Platelet Volume Biomarkers 030217 neurology & neurosurgery |
| Zdroj: | Journal of Craniofacial Surgery. 27:e575-e578 |
| ISSN: | 1049-2275 |
| Popis: | OBJECTIVES Cholesteatoma is a chronic inflammatory clinical disorder, and it may cause hearing loss and various complications due to its destructive nature. Mean platelet volume (MPV) is a prothrombotic and proinflammatory marker. The aim of this study is to investigate predictive values of MPV, neutrophil-to-lymphocyte ratio, erythrocyte distribution width, and platelet lymphocyte ratio in cholesteatomatous or noncholesteatomatous pediatric chronic otitis media. METHODS In this study, the authors retrospectively analyzed 24 patients with cholesteatomatous chronic otitis media, 9 patients with noncholesteatomatous chronic otitis media, and 36 age- and sex-matched healthy controls. Cholesteatomatous and noncholesteatomatous chronic otitis media groups were compared with each other, and with controls for WBC, MPV, erythrocyte distribution width, neutrophil-to-lymphocyte ratio, and platelet lymphocyte ratio. RESULTS Mean platelet volume was significantly lower in patients with cholesteatoma (8.17 ± 1.22 fL) compared with the control group (10.42 ± 0.87 fL) (P |
| Databáze: | OpenAIRE |
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