A possible flip-flop genetic mechanism for reciprocal gene expression
| Autor: | Giuseppina Maria Rosaria Russo, Giuseppe Geraci, Rossella Di Giaimo, Nicoletta Potenza, Maria Luisa Chiusano, Rosanna del Gaudio |
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| Přispěvatelé: | Chiusano, MARIA LUISA, DI GIAIMO, Rossella, Potenza, Nicoletta, Russo, G. M. R., Geraci, Giuseppe, DEL GAUDIO, Rosanna, M. L., Chiusano, DI GIAIMO, R, Geraci, G, DEL GAUDIO, R., Nicoletta, Potenza, Giuseppina M. R., Russo |
| Jazyk: | angličtina |
| Rok vydání: | 2005 |
| Předmět: |
INNEXIN
CHAETOPTERUS VARIOPEDATUS Biophysics Nerve Tissue Proteins Innexin Biochemistry RNA interference Structural Biology POLYCHAETE Gene expression ANNELID Genetics Melanogaster Animals Drosophila Proteins Protein Isoforms GENE STRUCTURE ETEROGENEITY Molecular Biology Gene Genomic organization IN SITU HYBRIDIZATION EMBRYONIC DEVELOPMENT Gap junction protein biology GAP JUNCTION Gene Expression Regulation Developmental Membrane Proteins Cell Biology biology.organism_classification Transmembrane protein Cell biology Drosophila melanogaster Multigene Family |
| Popis: | Innexins are a family of transmembrane proteins involved in the formation of gap junctions, specific intercellular channels, in invertebrates. Analyses of the entire innexin family during Drosophila melanogaster embryonic development shows the occurrence of complex and specific patterns of expression of the different genes. Innexins inx-2 and inx-7, in general, do not appear to exhibit extensive co-expression in different D. melanogaster cellular compartments. We propose here a new and robust mechanism, based on our analysis of the genomic organization of inx-2 and inx-7, that structurally justifies the reciprocal expression of genes. © 2005 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved. |
| Databáze: | OpenAIRE |
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